I am a biochemist and cancer biologist with research focuses on lung cancer and how the disruption of intracellular signalling networks, primarily through the critical STAT family of proteins, contribute to cancer. I completed my BSc (2000) and BSc (Hons) (2001) in the Department of Pathology at the University of Melbourne, and PhD (2006) at the Peter MacCallum Cancer Centre. I then undertook postdoctoral training at New York University in the laboratory of Professor David E Levy. During this time, I discovered a mitochondrial pool of STAT3 that is necessary for cancers driven by Ras mutation (Gough et. al., Science. 2009 and Gough et.al., Blood. 2014).  In 2012, I was recruited back to Australia to start my independent laboratory. Our research takes advantage of sophisticated protein chemistry, functional genomics, molecular biology, and drug screening to define fundamental alterations in signal transduction pathways which are interrogated in mouse models of lung cancer (genetically engineered, xenograft and patient derived xenograft) to identify targetable alterations. Current research questions in my group include identifying mechanisms of platinum resistance and drugs to combat resistant lung cancer and the role(s) of tumour-immune interactions in controlling primary and metastatic disease.