Invited speakerOral presentationIndustryPanel / Q&A
Wednesday 18 November
MCG, Melbourne8:30AM - 9:00AM
Arrival & Registration
Betty Cuthbert Lounge
9:00AM - 9:15AM
Welcome
Olympic Room
9:15AM - 9:55AM
Matthew Krummel - Krummel Lab, University Of California San Francisco
Announcing Soon
9:55AM - 10:15AM
Sapna Devi - University Of Melbourne
Neural control of the tumour ecosystem in breast cancer
10:15AM - 10:30AM
Ashray Gunjur
Gut Fusobacterium animalis correlates with poor combination immune
checkpoint blockade efficacy in advanced biliary tract cancer
10:30AM - 10:45AM
Xiao Jing (XJ) Ong
An off-the-shelf KIR3DL2-directed CAR-T cells for T-cell lymphomas:
Overcoming safety, manufacturing barriers and antigen escape
10:45AM - 11:00AM
Lewis Newland
IFNɣ impedes CD8+ T cell control of metastatic melanoma in
tumour-draining lymph nodes
11:00AM - 11:30AM
Morning Tea
Betty Cuthbert Lounge
11:30AM - 12:00PM
Di Yu - University Of Queensland
Ferroptosis in T Cells: From Mechanism to Therapeutic Opportunity
12:00PM - 12:20PM
Sophia Davidson - Hudson Institute Of Medical Research
Developing novel therapeutics to regulate inflammation and cell stress in
models of neurodegeneration
12:20PM - 12:40PM
Rimma Goldberg - Monash University
Engineered food antigen specific T regulatory cells are a potential cell therapy for inflammatory bowel disease
12:40PM - 1:00PM
Claudia A Nold-Petry
Repurposing Anakinra (Interleukin-1 receptor antagonist) for Early-Life
Inflammatory Diseases in Extremely Preterm Infants
1:00PM - 2:00PM
Lunch
Betty Cuthbert Lounge
2:00PM - 2:30PM
Claire Borg - Moderna
Programming the Immune System for Cancer
2:30PM - 2:50PM
Christophe CM Macri
Exploiting dendritic cell biology with next-generation mRNA-lipid
nanoparticle vaccines
2:50PM - 3:00PM
Alicia K Yong
Development of a Novel mRNA Vaccine for Alzheimer’s Disease
3:00PM - 3:30PM
Dr Sarah Herridge & Dr Simon Hardwick - BioNTech
Accelerating Research Translation of mRNA-Based Innovation
3:30PM - 4:00PM
Afternoon Tea
Betty Cuthbert Lounge
4:00PM - 5:00PM
Laureate Professor Emeritus Peter Doherty
Announcing Soon
5:00PM - 7:00PM
Poster Session I
Betty Cuthbert Lounge
7:00PM - 10:00PM
Conference Dinner
Olympic Room
Professor Georgina Long
Curing the third space: cancer is real, so who needs what and by when?
Melanoma Institute Australia, The University of Sydney, North Sydney, NSW,
Australia
Checkpoint inhibitor immunotherapy, and now mRNA-based personalised vaccines
have transformed melanoma, yet many patients are still not cured and die of
their disease. Progress for these patients, the third space, is slowed not only
by the time it takes to understand the biology and develop effective new
therapies, but by how oncology is practised: legacy drugs that anchor trial
design, endpoints that take years to mature, and a caution rooted in “first, do
no harm” that can become a fear of doing worse, even where the disease offers
little worse to fear. What does the field need to accelerate?
Thursday 19 November
MCG, Melbourne9:00AM - 9:40AM
Kim Good-Jacobson - Monash Biomedicine Discovery Institute
Memory B cells and plasma cells in chronic infectious disease
9:40AM - 10:00AM
Matthew J Worley
Establishing an iPSC Derived Lung Triple Culture to Model Viral
Exacerbations of COPD and Preschool Wheeze
10:00AM - 10:30AM
Simon Phipps - QIMR Berghofer
How breast milk components influence neonatal immunity in the lung
10:30AM - 11:00AM
Morning Tea
Betty Cuthbert Lounge
11:00AM - 11:20AM
Samuel Forster - Hudson Institute Of Medical Research
Announcing Soon
11:20AM - 11:40AM
Misty Jenkins - Walter And Eliza Hall Institute Of Medical Research
Announcing Soon
11:40AM - 12:00PM
David Khoury - Kirby Institute, UNSW
Pre-clinical data in vaccine development, assessment and deployment
12:00PM - 12:30PM
Q & A Panel
With Samuel Forster, Misty Jenkins and David Khoury
12:30PM - 2:00PM
Lunch
Betty Cuthbert Lounge
2:00PM - 2:30PM
Sherene Loi - Peter Maccallum Cancer Centre
Rethinking immune responses in breast cancer
2:30PM - 2:45PM
Louis Perriman
iPSC generated γδ T cells for the production of an ‘off-the-shelf’ cellular
therapy to treat human disease.
2:45PM - 3:00PM
Kayla R Wilson
A new immunometabolic checkpoint for CD8+ T cell immunity
3:00PM - 3:30PM
Cameron Turtle - The University Of Sydney
Clinical trials of CD19 CAR-T cell immunotherapies
3:30PM - 4:00PM
Afternoon Tea
Betty Cuthbert Lounge
4:00PM - 4:30PM
Siok Tey - Royal Brisbane And Women’s Hospital & QIMR Berghofer
Announcing Soon
4:30PM - 5:00PM
Charles Swanton - Francis Crick Institute & UCL Cancer Institute
Announcing Soon
5:00PM - 5:10PM
Prizes & Concluding Remarks
Olympic Room
Poster List
Poster Session I · Wednesday 18 November
75 posters
#101
Mohammadreza Mohamadreza Sheikh Sheikh Sajjadieh
Membrane Dynamics Index Identifies Immune-Inflamed and Immune-Desert States in
Lung Adenocarcinoma
#102
Le Hoang
Exploring STING response within dendritic cells to improve immunotherapy
efficacy
#103
Georgia Dow
Investigating CD4+ and CD8+ T cell responses to a nested
peptide
#104
Janin Chandra
Circulating CD5⁺ dendritic cells link gut microbiome function to immunotherapy
response in cancer patients
#105
Simon Manuel ST Tria
Co-culture platform of patient derived organoids and autologous T cells to
discover novel immunotherapeutic options
#106
Venkateswar Addala
Tumour antigen atlas for paediatric brain cancer vaccine development
#107
Aditya Manna
Financial Toxicity and Access Barriers to Cancer Immunotherapy in Low- and
Middle-Income Countries: Perspectives from Rural Eastern India
#108
Shiyi Wu
Leveraging mRNA–LNP Technology for In Vivo CAR Immune-Cell Engineering
#109
Gabriel Goncalves
Circulating HLA Ligandomes Reflect Tumour Antigen Landscapes in Pathological
Non-Responding (pNR) Melanoma Treated with Neoadjuvant Immune Checkpoint
Inhibitors (ICI).
#111
Wanxiaojie Xie
Preclinical Evaluation of Cytokine-Adjuvanted Multivalent MVA Vaccines
Encoding Influenza A Virus and SARS-CoV-2 Antigens
#112
Rachel Song
From Throat to Skin: Bacteria-Triggered Autoimmunity Shaped by Genetic
Susceptibility
#113
Zoe Magill
The unintended effects of melanoma targeted therapies on dendritic
cell-mediated immune responses
#114
Misty R Jenkins
Tumour-directed PD-L1×CD137 bispecific immunomodulation unlocks curative
multi-target CAR T cell therapy in glioblastoma
#115
Misty R Jenkins
PDGFRa-CAR T cells induce sustained remission in a representative model of
disseminated pediatric high-grade glioma
#116
Danielle Blud
Optimising a machine learning algorithm for immunotherapy target
identification in brain cancer
#117
Ludivine Grzelak
Revealing dose and repeat effects of a novel Influenza vaccine on humoral
immunity
#118
Jin Ng
Understanding the Role of γδ T Cells in Immunotherapy Responses in Small Cell
Lung Cancer
#119
Milie M Desai
Exploring CAR T cell therapy and immunomodulatory agents in immunocompetent
paediatric brain cancer models
#120
Vivian Tran
Integrating human and experimental models to identify immune mechanisms
underlying cardiovascular complications in Long COVID.
#121
Javad Masoumi
Identification of shared immunogenic non-canonical HLA-A*02:01-presented
peptides for therapeutic cancer vaccine development in BRCA-deficient breast
cancer
#122
Matilda Doran
Microbiota-derived choline metabolites improve CD8+ T cell
responses and correlate with ICI efficacy in melanoma patients
#123
Maleika Osman
Precision engineering of CAR-T cells for tumour-restricted secretion of
cytokines in a novel syngeneic multiple myeloma model
#124
Laila Karra Khalil
A novel allogeneic Tissue Factor-targeted CAR-NK cell therapy for
endometriosis
#125
Tima Shamekhi
Antigen discovery for cancer immunotherapy in paediatric diffuse midline
glioma: from H3K27M neoantigens to dark antigens
#126
Anurag Adhikari
Immune Biomarkers Reveal Divergent Cellular and Humoral Responses Following
Repeated Pfizer SARS-CoV-2 Booster Vaccination
#127
Keziah Ting
RNA-Seq profiling demonstrates enhanced cytotoxicity, persistence and
manufacturing consistency in CTH-401, a late-preclinical-stage off-the-shelf
CAR NK cell product.
#128
Sining Li
Persistent low antigen during chronic infection sustains potent CD8+ effector
T cell responses that drive severe immunopathology
#129
Elham Shokati
A Single Cell Transcriptomic Atlas of CD8+ Cytokine-Induced Killer Cells from
Metastatic Colorectal Cancer Patients
#130
Ashleigh S Davey
Structural tuning of CAR potency for tailored anti-CD19 CAR-T cell therapies
#131
Yoseph Adel YW Wahba Molano
A patient-derived CAM platform for rapid evaluation of glioblastoma therapies
and future modelling of tumour–immune interactions
#132
Farnaz Fahimi
Development of monoallelic cell lines with non-classical HLAs
#133
Purva Trivedi
Myeloid cell-specific HCK shapes fibrotic tumour microenvironment in
pancreatic cancer through macrophage-fibroblast crosstalk
#134
Hannah Walker
immune profiling reveals upregulation of profibrotic & JAK-STAT signalling as
a mediator of post-HSCT lung complications in children
#135
Brittany Doran
Preclinical development of tissue factor-targeted iPSC-derived CAR-NK cells
for solid tumours
#136
Ryan s Cross
Designing Novel Versatile Protease Regulatable Chimeric Antigen Receptor
(VIPER) T Cell Therapies For High Grade Glioma
#137
Harry L Horsnell
Local Invasion of Melanoma Metastasis into Lymph Nodes Drives Spatially
Restricted Immunosuppressive Niches Underpinned by Distinct Fibroblastic
Populations
#138
Kiho Tanaka
Establishment of advanced human immune system mouse models
#139
Abhinaya Muraly
Butyrate-Driven Memory Precursor CD8⁺ T Cell Differentiation Requires Fatty
Acid Synthesis
#140
Lacey Klompmaker
Treatment with recombinant IFNe induces a rapid interferon response in human
endometrial epithelial organoids
#141
Jamie Tuibeo
Investigation of the immune response to HIV in a Nepalese cohort
#142
Chloe E Jackson
Microbiota-mediated epithelial crosstalk and IL-21-Stat3 signalling in γδ T
Cells for improved immunotherapy in colorectal cancer
#143
Presenter announcing soon
Investigating Vδ1+ γδ T Cells in Primary Thymus and Artificial
Thymic Organoids for Immunotherapeutic Applications
#144
Yannick Alexandre
The splenic fibroblastic microenvironment regulates exhausted T cell responses
during chronic infection and checkpoint blockade
#145
Tina Z Zhang
Leveraging the Therapeutic Potential of Human Vδ3+ T Cells
#146
Anuratha Sakthianandeswaren
Patient Derived Tumour Organoid (PDTOs) models to advance immunotherapy
approaches for Oral Squamous Cell Carcinoma (OSCC)
#147
Ryan S Cross
HSP90B1 targeting Chimeric Antigen Receptor (CAR) T cell therapy is effective
in the treatment of solid tumours
#148
Zahra Taylor
Comparing therapeutic immunosuppression by the CTLA4-Ig fusion proteins
abatacept and belatacept
#149
Daniel T Utzschneider
B cell lymphoma promotes regulatory T cell response to escape CD4+
T cell-mediated cytotoxicity and responses to checkpoint blockade
#150
Yuxi Cao
Follicular T cell program including CXCR5 and ICOS regulates exhausted T cell
responses to chronic infection and cancer
#151
Galih GA Adhyatma
Suppressing the suppressors – new antibody strategies in cancer immunotherapy
#152
Xiaomin Wang
Structural and Functional Characterisation of LRRC15 Recognition by
Therapeutic Monoclonal Antibody and Engineered Minibinders
#154
Bahar Naseri
Preclinical evaluation of a Clec9A-targeted polyhydroxybutyrate nanovaccine
for cancer immunotherapy
#155
Maximilien Evrard
Spatially organised danger sensing selectively remodels intestinal
tissue-resident lymphocytes
#158
Liam Neil
Employing Natural Killer Cells to Reveal Weaknesses in Breast Cancer
#159
Hugh Chalmers
Developing an ex vivo tissue platform to predict patient response to
neo-adjuvant immunotherapy for triple negative breast cancer.
#160
Mark R Dowling
ctDNA-directed intervention with epcoritamab alone or in combination with
lenalidomide and rituximab is feasible in the early post-CAR-T population at
high risk of relapse: Interim results from EpLCART
#162
Rifqa Fayaz
Investigating changes in the absence of the cytokine negative regulator
Cytokine-Inducible SH2-Containing Protein (CISH) following influenza A virus
infection
#163
Yasmin M Lewis
Combination PD-1/CTLA-4 blockade diminishes the ovarian reserve, extends time
to natural conception and impairs early offspring growth in mice.
#164
Mark R. Dowling
A signature of early myeloid and endothelial activation in severe ICANS
derived from high-dimensional serum proteomics
#165
Cindy CA Audiger
A clinical grade type 1 dendritic cell manufacturing leveraging BATF3
expression and notch signalling
#166
Thiago Maass Steiner
Tumour microenvironments supporting close tumour–T-cell interactions and CD4⁺
T-cell cytotoxic differentiation underpin response to glofitamab in diffuse
large B-cell lymphoma
#167
Pailene S Lim
Identifying multi-stage vaccine targets against
Plasmodium falciparum malaria
#168
Evie Van Emmerik
Developing a Stem Cell Derived Human Alveolar Epithelial Model
#169
Jasmine JM Chuah
IFNε: A Novel Immunomodulator in High-Grade Serous Ovarian Cancer
#170
Md Jahangir Alam
Targeted depletion of CX3CR1+ immune cells attenuates joint and
skin inflammation in mouse models of rheumatoid arthritis and atopic
dermatitis
#171
Seyed Mohammad MJ Javadzadeh
Development of Spatial Immunopeptidomics for Tissue-Resolved Mapping of
Antigen Presentation
#172
Yining Tian
Genomic Alterations in TNF-Related Cell Death Pathways as Potential Biomarkers
for Personalized Therapy in Oral Squamous Cell Carcinoma
#173
Nancy Wang
B cells play an essential role in programming CD4⁺ T cell memory development
following intracellular bacterial infection
#174
Anju Abraham
Mapping the Development of Protective Immunity and Relapse Risk in
Plasmodium vivax Using Longitudinal Systems Immunology
#175
Lorraine A O'Reilly
Cell death therapy tailored combination with CAR T-cells or conventional
treatment for late-stage head and neck cancer
#176
Shengbo Zhang
CAR-DC1: A novel next-generation dendritic cell therapy for targeting solid
tumours
#177
Kellie Mouchemore
Using spatial transcriptomics and machine learning to identify biomarkers of
immunotherapy response in TNBC
#178
Sanjay Sondekoppa Gopala Krishna
Computational identification and validation of cancer-specific neoantigens
using CAN-IMMUNE
#179
Matthias Ernst
Inhibition of IL6 trans-signalling rewires the immune-suppressive
myeloid compartment, limits liver metastases and identifies actionable colon
cancer patients
No posters match your search.